Author

Y.-J. Tan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:human· 2 Research Focus:drug response / drug discovery· 1 Assay:flow cytometry· 1 Organism:mouse· 1 Assay:protein sequence· 1 Assay:protein structure· 1

Frequent Co-Authors

A. Bertoletti· 2 shared A. Chia· 2 shared A. T. Tan· 2 shared K. Kunasegaran· 2 shared L.-F. Wang· 2 shared N. K. Mohd-Ismail· 2 shared N. Le Bert· 2 shared P. A. Tambyah· 2 shared

Activity by Year

2020-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersImmunology

A. Bertoletti

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Next generation vaccine platform: polymersomes as stable nanocarriers for a highly immunogenic and durable SARS-CoV-2 spike protein subunit vaccine

J. H. Lam, A. K. Khan, T. A. Cornell, R. J. Dress, T. W. Chia, W. W. W. Yeow, N. K. Mohd-Ismail, S. Venkatraman, K. T. Ng, Y.-J. Tan, D. E. Anderson, F. Ginhoux, M. Nallani

This paper develops a subunit vaccine using polymersomes to deliver SARS-CoV-2 spike protein and CpG adjuvant, showing robust and durable immune responses in mice.

bioRxiv · Jan 24, 2021 · PreprintImmunology

Highly functional virus-specific cellular immune response in asymptomatic SARS-CoV-2 infection

N. Le Bert, H. E. Clapham, A. T. Tan, W. N. Chia, C. Y. Tham, J. M. Lim, K. Kunasegaran, L. Tan, C.-A. Dutertre, N. Shankar, J. M. Lim, L. J. Sun, M. Zahari, Z. M. Tun, V. Kumar, , C. C. Tam

This study compares T cell responses in asymptomatic and symptomatic SARS-CoV-2感染者, finding that asymptomatic individuals have a robust and functional immune response with balanced cytokine production.

bioRxiv · Nov 25, 2020Immunology

Monoclonal antibodies for the S2 subunit of spike of SARS-CoV cross-react with the newly-emerged SARS-CoV-2

Z. Zheng, V. M. Monteil, S. Maurer-Stroh, C. W. Yew, C. Leong, N. K. Mohd-Ismail, S. C. Arularasu, V. T. K. Chow, R. T. P. Lin, A. Mirazimi, W. Hong, Y.-J. Tan

This study shows that monoclonal antibodies against SARS-CoV's S2 subunit cross-react with SARS-CoV-2, highlighting sequence conservation and potential utility in diagnostics.

Eurosurveillance · Jul 16, 2020Peer-reviewedMicrobiology

Different pattern of pre-existing SARS-COV-2 specific T cell immunity in SARS-recovered and uninfected individuals

N. Le Bert, A. T. Tan, K. Kunasegaran, C. Y. L. Tham, M. Hafezi, A. Chia, M. Chng, M. Lin, N. Tan, M. Linster, W. N. Chia, M. I.-C. Chen, L.-F. Wang, E. E. Ooi, S. Kalimuddin, , A. Bertoletti

The paper compares pre-existing SARS-CoV-2 specific T cell immunity in SARS-recovered and uninfected individuals, finding differential T cell immunodominance patterns.

bioRxiv · May 26, 2020Immunology