Structure-activity mapping of the force- and sequence-dependent landscape of T cell activation
Y. Feng, X. Zhao, A. K. White, K. C. Garcia, P. M. Fordyce
This paper introduces BATTLES, a high-throughput method that applies biomechanical force to screen pMHCs for T-cell activation, revealing force- and sequence-dependent responses.
bioRxiv · Apr 24, 2021 · PreprintBiophysics