A biomimetic five-module chimeric antigen receptor (5MCAR) designed to target and eliminate antigen-specific T cells
S. Kobayashi, M. A. Thelin, H. L. Parrish, N. R. Deshpande, M. S. Lee, A. Karimzadeh, M. A. Niewczas, T. Serwold, M. S. Kuhns
This paper designs a biomimetic 5MCAR to target and eliminate antigen-specific T cells, showing it can mitigate type I diabetes in NOD mice.
bioRxiv · Jan 24, 2020Bioengineering