Author

A. Konrad

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:C. elegans· 3 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:variant calling· 2 Assay:whole-genome sequencing· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1

Frequent Co-Authors

U. Bergthorsson· 3 shared V. Katju· 3 shared T. C. Deiss· 2 shared D. Güleresi· 1 shared I. Gordo· 1 shared M. J. Brady· 1 shared M. Lässig· 1 shared N. Frazao· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 11 mutual co-author links

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3 shared papersEvolutionary Biology

U. Bergthorsson

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4 papers

Recent·Most cited

Two modes of evolution shape bacterial strain diversity in the gut for thousands of generations

N. Frazao, A. Konrad, D. Güleresi, M. Lässig, I. Gordo

This study shows that two evolutionary modes shape bacterial strain diversity in the gut over thousands of generations, with diversifying selection leading to ecotype coexistence and directional selection causing selective sweeps.

bioRxiv · Jan 11, 2022Evolutionary Biology

Mutation rate and spectrum in Caenorhabditis elegans mutation accumulation lines subjected to RNAi-induced knockdown of the mismatch repair gene msh-2

V. Katju, A. Konrad, T. C. Deiss, U. Bergthorsson

This study evaluates mutation rate and spectrum in C. elegans with impaired MMR gene msh-2, finding increased base substitutions and indels, but no change in mtDNA or copy-number variation of single-copy genes.

bioRxiv · Jul 12, 2021Evolutionary Biology

Global Gene Expression Divergence in Spontaneous Mutation Accumulation Lines of Caenorhabditis elegans under Varying Efficiency of Selection

T. C. Deiss, A. Konrad, U. Bergthorsson, V. Katju

This study examines how varying selection efficiency affects gene expression divergence in C. elegans mutation accumulation lines, finding increased transcriptional noise and specific pathway overexpression under low selection.

bioRxiv · May 3, 2021 · PreprintEvolutionary Biology

Mutational Landscape of Spontaneous Base Substitutions and Small Indels in Experimental Caenorhabditis elegans Populations of Differing Size

A. Konrad, M. J. Brady, U. Bergthorsson, V. Katju

The paper investigates mutation rates and fitness effects in C. elegans populations of different sizes, finding no correlation between mutation frequency and population size for base substitutions and small indels.

bioRxiv · Jan 23, 2019Evolutionary Biology