Mechanism Underlying the Immune Responses of a Sublingual Vaccine for SARS-CoV-2 with RBD Antigen and Adjuvant, Poly(I:C) or AddaS03, in Non-human Primates
T. Yamamoto, F. Mitsunaga, K. Wasaki, A. Kotani, K. Tajima, M. Tanji, S. Nakamura
This study evaluates the safety and immune response of a sublingual SARS-CoV-2 vaccine with RBD antigen and Poly(I:C) or AddaS03 adjuvant in non-human primates, finding Poly(I:C) induces a balanced immune response.
bioRxiv · May 15, 2023Immunology