Author

A. L. Koenig

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Research Focus:cell-cell communication· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Approach:deep learning· 1

Frequent Co-Authors

F. F. Kadyrov· 3 shared J. M. Amrute· 3 shared A. Kovacs· 2 shared C. J. Weinheimer· 2 shared D. Kreisel· 2 shared J. M. Nigro· 2 shared K. J. Lavine· 2 shared S. Yang· 2 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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3 shared papersImmunology

F. F. Kadyrov

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Genetic Mapping of Monocyte Fate Decisions Following Myocardial Infarction

A. L. Koenig, F. F. Kadyrov, J. M. Amrute, S. Yang, C. J. Weinheimer, J. M. Nigro, A. Kovacs, G. Smith, K. J. Lavine

The paper maps monocyte differentiation trajectories in the infarcted heart using genetic lineage tracing and single-cell RNA-sequencing, identifying a protective IFN-responsive macrophage subset.

bioRxiv · Dec 24, 2023Immunology

Targeting the Immune-Fibrosis Axis in Myocardial Infarction and Heart Failure

J. M. Amrute, X. Luo, V. Penna, A. Bredemeyer, T. Yamawaki, G. S. Heo, S. Shi, A. L. Koenig, S. Yang, F. F. Kadyrov, C. Jones, C. Kuppe, B. Kopecky, S. Hayat, P. Ma, , K. Lavine

The paper identifies a fibroblast trajectory associated with cardiac fibrosis and shows that macrophage-fibroblast crosstalk via IL-1β signaling drives fibrosis.

bioRxiv · Oct 17, 2022 · PreprintImmunology

Hypoxia Sensing in Resident Cardiac Macrophages Regulates Monocyte Fate Specification following Ischemic Heart Injury

F. F. Kadyrov, A. L. Koenig, J. M. Amrute, H. Dun, W. Li, C. J. Weinheimer, J. M. Nigro, A. Kovacs, A. L. Bredemeyer, L. Lai, B. J. Kopecky, V. Penna, D. Kreisel, K. J. Lavine

This study shows that hypoxia sensing in cardiac macrophages influences monocyte differentiation into inflammatory states after heart injury.

bioRxiv · Aug 4, 2022 · PreprintImmunology