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Primary ORCID profile (0000-0003-1948-9945 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints
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5 papers
Recent·Most cited
A. L. Koenig, F. F. Kadyrov, J. M. Amrute, S. Yang, C. J. Weinheimer, J. M. Nigro, A. Kovacs, G. Smith, K. J. Lavine
The paper maps monocyte differentiation trajectories in the infarcted heart using genetic lineage tracing and single-cell RNA-sequencing, identifying a protective IFN-responsive macrophage subset.
bioRxiv · Dec 24, 2023Immunology
F. F. Kadyrov, A. L. Koenig, J. M. Amrute, H. Dun, W. Li, C. J. Weinheimer, J. M. Nigro, A. Kovacs, A. L. Bredemeyer, L. Lai, B. J. Kopecky, V. Penna, D. Kreisel, K. J. Lavine
This study shows that hypoxia sensing in cardiac macrophages influences monocyte differentiation into inflammatory states after heart injury.
bioRxiv · Aug 4, 2022 · PreprintImmunology
N. R. Wong, J. Mohan, B. Kopecky, S. Guo, L. Du, J. Leid, O. Dmytrenko, H. Luehmann, G. Bajpai, L. Ewald, L. Bell, N. Patel, I. Lokshina, A. Bredemeyer, C. J. Weinheimer, , K. J. Lavine
This study identifies CCR2- resident cardiac macrophages as critical for adaptive myocardial remodeling in heart failure, showing their role in ventricular remodeling and coronary angiogenesis.
bioRxiv · Jan 28, 2021Immunology
A. L. Bailey, O. Dmytrenko, L. Greenberg, A. L. Bredemeyer, P. Ma, J. Liu, V. Penna, L. Lai, E. S. Winkler, S. Sviben, E. Brooks, A. P. Nair, K. A. Heck, A. S. Rali, L. Simpson, , K. J. Lavine
This study shows SARS-CoV-2 infects human engineered heart tissues, causing myocarditis-like features, and identifies ACE2 and proteases as entry factors.
bioRxiv · Nov 4, 2020Immunology
S. L. Brody, S. P. Gunsten, H. P. Luehmann, D. H. Sultan, M. Hoelscher, G. S. Heo, J. Pan, J. R. Koenitzer, E. C. Lee, T. Huang, C. Mpoy, S. Guo, R. Laforest, A. Salter, T. D. Russell, , Y. Liu
PET imaging of CCR2+ cells in lung fibrosis identifies therapeutic response in mouse models and shows perifibrotic signal in IPF patients.
bioRxiv · Mar 4, 2020Cell Biology