A. L. Starr

Disentangling cell-intrinsic and extrinsic factors underlying evolution

The paper decomposes evolutionary divergence into cell-intrinsic, extrinsic, and interaction components using reciprocal rat-mouse chimeras and finds cell-intrinsic factors dominate but extrinsic factors also play a role.

Cell type-specific cis-regulatory divergence in gene expression and chromatin accessibility revealed by human-chimpanzee hybrid cells

The paper identifies cell type-specific cis-regulatory divergence in gene expression and chromatin accessibility using human-chimpanzee hybrid cells across six cell types.

Accounting for cis-regulatory constraint prioritizes genes likely to affect species-specific traits

The paper identifies genes with constrained cis-regulation within species but divergent regulation between species using allele-specific RNA-seq data from human-chimpanzee hybrids.