H. Fraser

Loss of O-specific antigen shapes Pseudomonas aeruginosa population microbiogeography in murine preclinical pulmonary infection model

The paper investigates how O-specific antigen loss in Pseudomonas aeruginosa affects population dynamics and aggregate formation in a murine infection model.

Disentangling cell-intrinsic and extrinsic factors underlying evolution

The paper decomposes evolutionary divergence into cell-intrinsic, extrinsic, and interaction components using reciprocal rat-mouse chimeras and finds cell-intrinsic factors dominate but extrinsic factors also play a role.

Cis-regulatory changes in locomotor genes are associated with the evolution of burrowing behavior

This study identifies cis-regulatory changes in locomotor genes associated with burrowing behavior evolution in Peromyscus mice by comparing gene expression and allele-specific expression in hybrids and post-burrowing mice.

Detecting selection with a genetic cross

This paper introduces a new statistical test to detect lineage-specific selection using phenotypic data from genetic crosses, showing it is more powerful and requires fewer individuals than existing methods.