Author

A. Laederach

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Approach:graph neural network· 2 Research Focus:host-pathogen & immune response· 2 Organism:virus· 2 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Assay:long-read sequencing· 1

Frequent Co-Authors

A. Dey· 2 shared S. Yan· 2 shared T. Schlick· 2 shared A. Borodavka· 1 shared A. Coria· 1 shared A. Wienecke· 1 shared B. Dadonaite· 1 shared D. L. Bauer· 1 shared

Activity by Year

2017-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersBiochemistry

A. Dey

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

An intricate balancing act: Upstream and downstream frameshift co-regulatory elements

S. Lee, S. Yan, A. Dey, A. Laederach, T. Schlick

The paper investigates the RNA structures and interactions of the 5' and 3' regions of the SARS-CoV-2 frameshifting element, revealing their co-regulatory roles and implications for therapeutic interventions.

bioRxiv · Jun 27, 2024 · PreprintBiochemistry

Rotavirus RNA chaperone mediates global transcriptome-wide increase in RNA backbone flexibility

A. Coria, A. Wienecke, A. Borodavka, A. Laederach

The paper uses SHAPE-MaP to analyze rotavirus transcriptome structure with and without NSP2, finding increased RNA backbone flexibility rather than helix unwinding.

bioRxiv · Jan 4, 2022Biochemistry

To knot or not to knot: Multiple conformations of the SARS-CoV-2 frameshifting RNA element

T. Schlick, Q. Zhu, A. Dey, S. Jain, S. Yan, A. Laederach

The paper identifies multiple structural conformations of the SARS-CoV-2 frameshifting RNA element and their potential roles in viral replication and therapeutic targeting.

bioRxiv · Mar 31, 2021Biochemistry

The structure of the influenza A virus genome

B. Dadonaite, E. Barilaite, E. Fodor, A. Laederach, D. L. Bauer

This study maps RNA-RNA interactions in influenza A virus genomes, revealing a structured genome and redundant interactions that enable reassortment and packaging selectivity.

bioRxiv · Dec 21, 2017Microbiology