The E3/E4 ubiquitin conjugation factor UBE4B interacts with and ubiquitinates the HTLV-1 Tax oncoprotein to promote NF-kB activation
E. W. Harhaj, S. Mohanty, T. Han, Y. B. Choi, A. Lavorgna, J. Zhang
This study identifies UBE4B as a host factor that ubiquitinates HTLV-1 Tax to promote NF-κB activation and cell survival in ATLL.
PLOS Pathogens · Dec 23, 2020Peer-reviewedMicrobiology