A. Le Rouzic

Detecting directional epistasis and dominance from cross-line analyses in alpine populations of Arabidopsis thaliana

The paper examines non-additive genetic effects in Arabidopsis thaliana by analyzing crosses between inbred lines, finding mid-parent heterosis for biomass and outbreeding depression for siliques.

Correlated stabilizing selection shapes the topology of gene regulatory networks

This study shows that correlated selection influences gene regulatory network topology by shaping gene co-expression patterns through regulatory interactions and mutation effects.

A Population Genetics Theory for piRNA-regulatedTransposable Elements

This paper develops population genetics models incorporating piRNA regulation of transposable elements, showing new equilibrium dynamics compared to traditional models.

Gene network simulations provide testable predictions for the molecular domestication syndrome

The paper uses gene network simulations to predict molecular changes in domesticated plants compared to wild forms, identifying five key genetic architecture shifts.

Interplay between extreme drift and selectionintensities favors the fixation of beneficial mutations in selfing maize populations

The paper investigates how extreme drift and selection intensities affect mutation fixation in selfing maize populations, finding that beneficial mutations are enriched and small-effect mutations are facilitated by environmental stochasticity and selection variation.

Unidirectional response to bidirectional selection on body size. I. Phenotypic, life history and endocrine response.

This study shows that medaka fish evolve differently under selection for large vs. small body size, with asymmetric evolvability affecting growth, maturation, and reproductive traits.

Unidirectional response to bidirectional selection on body size. II Quantitative genetics.

The paper assesses the response to bivariate artificial selection on body size and maturity in medaka fish, finding discrepancies between observed and predicted evolutionary responses.

Differential Metabolic Sensitivity of Insulin-like-response- and mTORC1-Dependent Overgrowth in Drosophila Fat Cells

This study investigates the differential metabolic sensitivity of mTORC1- and Ilp-dependent overgrowth in Drosophila fat cells, showing distinct metabolic requirements and compensatory mechanisms.