Author

A. Leitao

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1 Research Focus:drug response / drug discovery· 1 Organism:mouse· 1

Frequent Co-Authors

A. Bhumkar· 1 shared A. Chappard· 1 shared C. A. Montanari· 1 shared C. D. Lopes· 1 shared C. Feldmann· 1 shared C. Lemke· 1 shared D. J. B. Hunter· 1 shared D. Y. Tezuka· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperBiochemistry

A. Bhumkar

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Selectivity of Protein Interactions along the Aggregation Pathway of a-Synuclein

A. Leitao, P. Rudolffi Soto, A. Chappard, A. Bhumkar, D. J. B. Hunter, E. Sierecki, Y. Gambin

This study maps protein interactions with different -SYN aggregation species, revealing selectivity in recruitment of LB components during aggregation.

bioRxiv · Jan 29, 2021Biochemistry

Constitutive activation of cellular immunity underlies the evolution of resistance to infection

A. Leitao, R. Arunkumar, J. P. Day, E. M. Geldman, F. M. Jiggins

The paper shows that Drosophila populations evolved resistance to parasitism by making immune-inducible genes constitutively active through the pre-differentiation of immune cells.

eLife · Dec 24, 2020Peer-reviewedEvolutionary Biology

Mapping the S1 and S1 subsites of cysteine proteases with new dipeptidyl nitrile inhibitors as trypanocidal agents

L. Cianni, C. Lemke, E. Gilberg, C. Feldmann, F. Rosini, F. d. R. Rocho, J. F. R. Ribeiro, D. Y. Tezuka, C. D. Lopes, S. de Albuquerque, J. Bajorath, A. Leitao, S. Laufer, M. Gütschow, C. A. Montanari

The paper designs and tests 26 dipeptidyl nitrile inhibitors against cysteine proteases to map their S1/S1' subsites and identify potential trypanocidal agents.

bioRxiv · Sep 8, 2019Biochemistry