Contribution of pretomanid to novel regimens containing bedaquiline with either linezolid or moxifloxacin and pyrazinamide in murine models of tuberculosis
J. Xu, S.-Y. Li, D. Almeida, R. Tasneen, K. Barnes-Boyle, P. J. Converse, A. M Upton, K. Mdluli, N. Fotouhi, E. Nuermberger
This study shows pretomanid improves the efficacy of TB treatment regimens in mice by reducing relapse and bedaquiline resistance.
bioRxiv · Jan 8, 2019Pharmacology & Toxicology