A. M. B. Lucas

Effects of calorie restriction on reactive oxygen species production by mitochondrial reverse electron transport, mitochondrial permeability transition pore, and beta-adrenergic stimulation during cardiac hypertrophy

This study investigates how calorie restriction affects mitochondrial function, oxidative stress, and beta-adrenergic signaling in cardiac hypertrophy, finding reduced ROS production and improved mitochondrial content but no change in beta-adrenergic insensitivity.

Calorie Restriction Maintains Mitochondrial Function and Redox Balance Avoiding Lipidomic Reprogramming during Isoproterenol-Induced Cardiac Hypertrophy

This study shows calorie restriction prevents cardiac hypertrophy-induced lipidomic changes, mitochondrial dysfunction, and oxidative stress in vivo.