Author

A. M. Gregus

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

B. Brown· 1 shared C. Miliano· 1 shared E. J. Olson· 1 shared E. S. Witze· 1 shared I. Chen· 1 shared K. A. Bustin· 1 shared K. A. Eddinger· 1 shared K. Hu· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperPharmacology & Toxicology

B. Brown

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2 papers

Recent·Most cited

12/15-Lipoxygenases mediate neuropathic-like pain hypersensitivity in female mice

B. Brown, I. Chen, C. Miliano, L. B. Murdaugh, Y. Dong, K. A. Eddinger, T. L. Yaksh, M. D. Burton, M. Buczynski, A. M. Gregus

This study shows that 12/15-Lipoxygenases contribute to neuropathic-like pain hypersensitivity in female mice, with inhibitors reversing pain symptoms.

bioRxiv · Apr 4, 2024 · PreprintPharmacology & Toxicology

Hydrazines as versatile chemical biology probes and drug-discovery tools for cofactor-dependent enzymes

Z. Lin, X. Wang, K. A. Bustin, L. He, R. M. Suciu, N. Schek, M. Ahmadi, K. Hu, E. J. Olson, W. H. Parsons, E. S. Witze, P. D. Morton, A. M. Gregus, M. W. Buczynski, M. L. Matthews

This paper introduces hydrazine-based chemoproteomic probes to target cofactor-dependent enzymes, enabling enzyme discovery and drug development through diverse functional profiling.

bioRxiv · Jun 17, 2020 · PreprintBiochemistry