Author

A. M. Hogan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:bacteria (other)· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

S. T. Cardona· 4 shared A. Motnenko· 2 shared A. S. M. Z. Rahman· 2 shared A. Bosch· 1 shared A. Canney· 1 shared A. E. Ryan· 1 shared A. Natarajan· 1 shared B. Leon· 1 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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4 shared papersMicrobiology

S. T. Cardona

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Cell envelope structural and functional contributions to antibiotic resistance in Burkholderia cenocepacia

A. M. Hogan, A. Motnenko, A. S. M. Z. Rahman, S. T. Cardona

This study identifies cell envelope structures and functions critical for antibiotic resistance in Burkholderia cenocepacia through a re-analysis of transposon mutant data.

bioRxiv · Jan 3, 2024 · PreprintMicrobiology

Profiling cell envelope-antibiotic interactions reveals vulnerabilities to β-lactams in a multidrug-resistant bacterium

A. M. Hogan, A. Natarajan, D. T. Maydaniuk, B. Leon, Z. Batun, A. Motnenko, A. Bosch, S. T. Cardona

This study identifies cell envelope-associated resistance and susceptibility determinants in Burkholderia cenocepacia using transposon mutagenesis and antibiotic profiling, revealing new vulnerabilities to β-lactams and the mechanism of cefiderocol.

Nature Communications · Aug 9, 2023Peer-reviewedMicrobiology

New auranofin analogs with antibacterial properties against Burkholderia clinical isolates

D. Maydaniuk, B. Wu, D. Truong, S. H. Liyanage, A. M. Hogan, Z. L. Yap, M. Yan, S. T. Cardona

This study identifies two auranofin analogs, MS-40S and MS-40, with antibacterial activity against Burkholderia clinical isolates, including B. cenocepacia, and low toxicity in model organisms.

bioRxiv · Sep 10, 2021Microbiology

Stromal cell sialylation suppresses T cells in inflammatory tumour microenvironments: A new tumour stromal cell immune checkpoint?

H. Egan, O. Treacy, K. Lynch, N. A. Leonard, G. O'Malley, K. DeVeirman, K. Vanderkerken, M. Craughwell, L. J. Egan, T. Ritter, A. M. Hogan, K. Redmond, M. Sheehan, A. Canney, S. Hynes, , A. E. Ryan

This study shows that sialylation of stromal cells in tumors enhances immunosuppression and that targeting this process can reverse immune cell exhaustion.

bioRxiv · Jun 18, 2021 · PreprintImmunology

A broad-host-range CRISPRi toolkit for silencing gene expression in Burkholderia

A. M. Hogan, A. S. M. Z. Rahman, T. L. Lightly, S. T. Cardona

This paper develops a broad-host-range CRISPRi toolkit for gene silencing in Burkholderia species, demonstrating its utility in studying gene function and pathogenicity.

bioRxiv · Aug 16, 2019Microbiology