Author

K. Lynch

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Animal Behavior & Cognition· 2 Immunology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

A. Pellicano· 2 shared A. Bodansky· 1 shared A. Canney· 1 shared A. E. Ryan· 1 shared A. F. Kung· 1 shared A. Gaglio· 1 shared A. M. Hogan· 1 shared A. Mitchell· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersAnimal Behavior & Cognition

A. Pellicano

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Autoantibody discovery across monogenic, acquired, and COVID19-associated autoimmunity with scalable PhIP-Seq

S. E. Vazquez, S. A. Mann, A. Bodansky, A. F. Kung, Z. Quandt, E. M. N. Ferre, N. Landegren, D. Eriksson, P. Bastard, S.-Y. Zhang, J. Liu, A. Mitchell, C. Mandel-Brehm, B. Miao, G. Sowa, , J. L. DeRisi

This paper scales PhIP-Seq for autoantibody discovery across multiple autoimmune diseases and COVID19, enabling machine learning predictions and identification of disease-specific autoantigens.

bioRxiv · Mar 23, 2022Immunology

Stromal cell sialylation suppresses T cells in inflammatory tumour microenvironments: A new tumour stromal cell immune checkpoint?

H. Egan, O. Treacy, K. Lynch, N. A. Leonard, G. O'Malley, K. DeVeirman, K. Vanderkerken, M. Craughwell, L. J. Egan, T. Ritter, A. M. Hogan, K. Redmond, M. Sheehan, A. Canney, S. Hynes, , A. E. Ryan

This study shows that sialylation of stromal cells in tumors enhances immunosuppression and that targeting this process can reverse immune cell exhaustion.

bioRxiv · Jun 18, 2021 · PreprintImmunology

Discrete Community Assemblages Within Hypersaline Paleolake Sediments of Pilot Valley, Utah

K. Lynch, K. Rey, R. Bond, J. Biddle, J. Spear, F. Rosenzweig, J. Munakata Marr

This study analyzes microbial communities in hypersaline paleolake sediments of Pilot Valley, Utah, revealing three discrete community groups and potential halophilicity in Gemmatimonadetes.

bioRxiv · May 30, 2019 · PreprintMicrobiology

Socially regulated estrogen in an eavesdropping brood parasite

K. Lynch, G. Azieva, A. Pellicano

This study shows that vocal signals from both conspecific and heterospecific hosts increase estrogen levels in female brown-headed cowbirds, indicating social cues influence reproductive physiology.

bioRxiv · Jul 10, 2018Animal Behavior & Cognition

Losing maternal care: Neotenic gene expression in the preoptic area of avian brood parasites

K. Lynch, L. O'Connell, M. Louder, A. Pellicano, A. Gaglio, A. Xiang, C. Balakrishnan, E. Fischer

The paper compares gene expression in the preoptic area of brood parasitic and non-parasitic birds to investigate molecular mechanisms of maternal behavior loss, finding evidence for neotenic gene expression.

bioRxiv · Jun 16, 2018Animal Behavior & Cognition