The ER membrane protein complex is required to ensure correct topology and stable expression of flavivirus polyproteins
A. M. Ngo, M. J. Shurtleff, K. D. Popova, J. Kulsuptrakul, J. S. Weissman, A. S. Puschnik
This study shows the ER membrane protein complex is essential for correct topology and stable expression of flavivirus polyproteins by preventing degradation of NS4A-NS4B.
bioRxiv · Sep 4, 2019Microbiology