A conserved Plasmodium protein that localizes to liver stage nuclei is critical for late liver stage development.
D. Goswami, S. A. Arredondo, W. Betz, J. Armstrong, K. M. Z. Oualim, A. M. Seilie, S. C. Murphy, S. H. I. Kappe, A. M. Vaughan
This paper identifies a Plasmodium protein, LINUP, critical for late liver stage development and shows its deletion causes severe attenuation of liver-to-blood stage transition in both P. yoelii and P. falciparum.
bioRxiv · Dec 13, 2022 · PreprintCell Biology