A. M. Vaughan

Potent AMA1-specific human monoclonal antibody against P. vivax Pre-erythrocytic and Blood Stages

The paper isolates a human monoclonal antibody that targets Plasmodium vivax AMA1, blocking both pre-erythrocytic and blood stage infections.

Global gene expression of human malaria parasite liver stages throughout intrahepatocytic development

This study provides the first comprehensive gene expression profile of Plasmodium falciparum liver stages during in vivo development, revealing key metabolic and regulatory processes.

A conserved Plasmodium protein that localizes to liver stage nuclei is critical for late liver stage development.

This paper identifies a Plasmodium protein, LINUP, critical for late liver stage development and shows its deletion causes severe attenuation of liver-to-blood stage transition in both P. yoelii and P. falciparum.

Plasmodium GPI-Anchored Micronemal Antigen is essential for parasite transmission through the mosquito host

This study shows that GAMA is essential for Plasmodium sporozoite motility, egress from oocysts, and invasion of the vertebrate host, with distinct roles in each process.

Plasmodium falciparum Calcium Dependent Protein Kinase 4 is critical for male gametogenesis and transmission to the mosquito vector

This study shows that PfCDPK4 is essential for male gametogenesis in Plasmodium falciparum, affecting exflagellation and parasite transmission to mosquitoes.