Phage-delivered CRISPR-Cas9 for strain-specific depletion and genomic deletions in the gut microbiome
K. N. Lam, P. Spanogiannopoulos, P. Soto-Perez, M. Alexander, M. J. Nalley, J. E. Bisanz, R. R. Nayak, A. M. Weakley, F. B. Yu, P. J. Turnbaugh
This study uses phage-delivered CRISPR-Cas9 to deplete specific E. coli strains and induce genomic deletions in the gut microbiome of mice.
Cell Reports · Nov 1, 2021Peer-reviewedMicrobiology