The Role of CD147 in Leukocyte Aggregation in Liver Injury
N. Main, C. Yee, A. Terry, I. Stevanovski, A. Maczurek, A. J. Morgan, S. Calabro, A. J. Potter, T. L. Iemma, D. G. Bowen, G. Ahlenstiel, F. J. Warner, G. W. McCaughan, S. V. McLennan, N. A. Shackel
This study identifies CD147 as a mediator of leukocyte aggregation in liver injury, showing that blocking CD147 reduces aggregate formation and liver damage without affecting overall leukocyte numbers.
bioRxiv · Apr 6, 2019Immunology