Author

G. W. McCaughan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:host-pathogen & immune response· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Assay:flow cytometry· 1

Frequent Co-Authors

H. E. Zhang· 2 shared M. D. Gorrell· 2 shared M. G. Gall· 2 shared S. V. McLennan· 2 shared A. Cook· 1 shared A. J. Lay· 1 shared A. J. Morgan· 1 shared A. J. Potter· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersPathology

H. E. Zhang

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Transplantation of high fat fed mouse microbiota into zebrafish larvae identifies MyD88-dependent acceleration of hyperlipidaemia by Gram positive cell wall components

P. M. Cholan, S. Morris, K. Luo, J. Chen, J. A. Boland, G. W. McCaughan, W. J. Britton, S. H. Oehlers

The paper transplants mouse high fat diet microbiota into zebrafish larvae to identify microbial factors that accelerate hyperlipidaemia via MyD88 signaling.

bioRxiv · Apr 28, 2021 · PreprintMicrobiology

The Role of CD147 in Leukocyte Aggregation in Liver Injury

N. Main, C. Yee, A. Terry, I. Stevanovski, A. Maczurek, A. J. Morgan, S. Calabro, A. J. Potter, T. L. Iemma, D. G. Bowen, G. Ahlenstiel, F. J. Warner, G. W. McCaughan, S. V. McLennan, N. A. Shackel

This study identifies CD147 as a mediator of leukocyte aggregation in liver injury, showing that blocking CD147 reduces aggregate formation and liver damage without affecting overall leukocyte numbers.

bioRxiv · Apr 6, 2019Immunology

Fibroblast activation protein enzyme deficiency prevents liver steatosis, insulin resistance and glucose intolerance and increases fibroblast growth factor-21 in diet induced obese mice

S. Chowdhury, S. Song, H. E. Zhang, X. M. Wang, M. G. Gall, D. M.-T. Yu, A. J. Lay, M. S.-W. Xiang, K. A. Evans, S. Wetzel, Y. Liu, B. Yau, A. L. Coppage, L. Lo, R. A. Stokes, , M. D. Gorrell

This study shows that FAP deficiency in diet-induced obese mice reduces liver steatosis, insulin resistance, and glucose intolerance while increasing FGF-21 levels.

bioRxiv · Nov 4, 2018 · PreprintPathology

Immune regeneration in irradiated mice is not impaired by the absence of DPP9 enzymatic activity

M. G. Gall, H. E. Zhang, A. Cook, C. J. Jolly, G. W. McCaughan, B. Roediger, M. D. Gorrell

This study shows that DPP9 enzymatic activity is not required for immune regeneration in irradiated mice, as hematopoietic stem cell engraftment and reconstitution remain unaffected.

bioRxiv · Oct 1, 2018Immunology