Alteration of cardiolipin-dependent mitochondrial coupling in muscle protects against obesity
A. Prola, J. Blondelle, A. Ratnam-Vandestienne, J. Piquereau, R. Denis, S. Guyot, H. Chauvin, A. Mourier, M. Letheule, M. Maurer, C. Henry, N. Khadhraoui, G. Courtin, N. Blanchard-Gutton, L. Guillaud, , F. Pilot-Storck
This study identifies Hacd1 as a regulator of mitochondrial membrane composition in muscle, showing that reduced mitochondrial coupling protects against obesity.
bioRxiv · Jul 26, 2019 · PreprintCell Biology