A. Mourier

A cellular assay to determine the fusion capacity of MFN2 variants linked to Charcot-Marie-Tooth type 2A

This paper develops a cellular assay to assess MFN2 variants' fusion capacity in CMT2A and shows correlation with computational predictions.

LIX1 controls digestive mesenchyme-derived cell fate decision by regulating cristae organization in mitochondria

This study shows LIX1 regulates mitochondrial cristae organization, affecting YAP1/TAZ and KIT levels, which influences GIST cell fate and proliferation.

ACTIN Anchors the Highly Oligomeric DRP1 at Mitochondria-Sarcoplasmic Reticulum Contact Sites in Adult Murine Heart: Its Functional Implication

This study shows DRP1 clusters at mitochondria-SR contact sites via β-actin, maintaining mitochondrial quality control in adult hearts despite reduced DRP1 levels.

MDH2 is a metabolic switch rewiring the fuelling of respiratory chain and TCA cycle

This study identifies MDH2 as a metabolic switch that regulates NADH oxidation in the respiratory chain and TCA cycle by modulating OAA production and complex I/II activity.

\"Metabolic contest\", a new way to control carbon source preference

The paper introduces a new mechanism called 'metabolic contest' that regulates carbon source preference in trypanosomes without nutrient sensing or signaling.

Alteration of cardiolipin-dependent mitochondrial coupling in muscle protects against obesity

This study identifies Hacd1 as a regulator of mitochondrial membrane composition in muscle, showing that reduced mitochondrial coupling protects against obesity.