M. Maurer

Label-free imaging of macrophage phenotypes and phagocytic activity in the human dermis in vivo using two-photon excited FLIM

This paper uses TPE-FLIM to visualize and classify macrophage phenotypes and phagocytic activity in human skin in vivo, with machine learning achieving high sensitivity and specificity.

Molecular Pathophysiology of Cardiac Injury and Cardiac Microthrombi in Fatal COVID-19: Insights from Clinico-histopathologic and Single Nuclei RNA Sequencing Analyses

This study identifies transcriptomic changes in cardiac fibroblasts associated with cardiac microthrombi in fatal COVID-19 through single nuclei RNA sequencing and clinical analyses.

PolyQ expansion does not alter the Huntingtin-HAP40 complex

This study shows that polyQ expansion in HTT does not change the structure of the HTT-HAP40 complex, as revealed by biophysical and cryo-EM analyses.

Alteration of cardiolipin-dependent mitochondrial coupling in muscle protects against obesity

This study identifies Hacd1 as a regulator of mitochondrial membrane composition in muscle, showing that reduced mitochondrial coupling protects against obesity.

The Aryl Hydrocarbon Receptor senses the Henna pigment Lawsone and mediates Yin-Yang effects on skin homeostasis

This study shows that Lawsone, a Henna pigment, activates the AhR receptor in skin cells, with both beneficial and harmful effects depending on the physiological context.