Author

A. Mankin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Assay:protein sequence· 1 Assay:structural biology· 1

Frequent Co-Authors

N. Vazquez-Laslop· 2 shared A. Di Stasi· 1 shared A. Mainz· 1 shared B. Beckert· 1 shared C. Crowe-McAuliffe· 1 shared D. Klepacki· 1 shared D. N. Wilson· 1 shared H. Paternoga· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiochemistry

N. Vazquez-Laslop

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2 papers

Recent·Most cited

Paenilamicins from the honey bee pathogen Paenibacillus larvae are context-specific translocation inhibitors of protein synthesis

T. O. Koller, M. J. Burger, M. Morici, H. Paternoga, T. Bulatov, A. Di Stasi, T. Dang, A. Mainz, K. Raulf, C. Crowe-McAuliffe, M. Scocchi, M. Mardirossian, B. Beckert, N. Vazquez-Laslop, A. Mankin, , D. N. Wilson

This study determines the structure of paenilamicin PamB2 bound to stalled ribosomes, revealing its mechanism as a context-specific translocation inhibitor of protein synthesis.

bioRxiv · May 21, 2024 · PreprintBiochemistry

Genome-wide effects of the antimicrobial peptide apidaecin on translation termination

K. Mangano, T. FLorin, X. Shao, D. Klepacki, I. Chelysheva, Z. Ignatova, Y. Gao, A. Mankin, N. Vazquez-Laslop

This study shows that the antimicrobial peptide apidaecin inhibits translation by arresting ribosomes at stop codons and causing stop codon bypass, leading to C-terminal extensions on proteins.

bioRxiv · May 17, 2020Biochemistry