Author

Z. Ignatova

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 2 Biophysics· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Assay:cryo-EM· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:protein folding & dynamics· 2 Organism:bacteria (other)· 1

Frequent Co-Authors

C. Crowe-McAuliffe· 2 shared C. Polte· 2 shared D. N. Wilson· 2 shared G. C. Atkinson· 2 shared H. Takada· 2 shared V. Murina· 2 shared A. C. O'Neill· 1 shared A. Kaffke· 1 shared

Activity by Year

2020-2024 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMicrobiology

C. Crowe-McAuliffe

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

The integrated stress response/eIF2α pathway controls cytokine production in tissue-resident memory CD4+ T cells

N. Asada, P. Ginsberg, H.-J. Paust, N. Song, J.-H. Riedel, J.-E. Turner, A. Peters, A. Kaffke, J. Engesser, H. Wang, Y. Zhao, P. Gild, R. Dahlem, S. Das, Z. Ignatova, , U. Panzer

This study shows that the ISR/eIF2α pathway regulates cytokine mRNA translation in Trm cells, limiting their activity in homeostasis but enabling rapid response during inflammation or autoimmunity.

bioRxiv · Jan 26, 2024Immunology

Structural basis of resistance to lincosamide, streptogramin A, and pleuromutilin antibiotics by ABCF ATPases in Gram-positive pathogens

C. Crowe-McAuliffe, V. Murina, K. J. Turnbull, M. Kasari, M. Mohamad, C. Polte, H. Takada, K. Vaitkevicius, J. Johansson, Z. Ignatova, G. C. Atkinson, A. C. O'Neill, V. Hauryliuk, D. N. Wilson

The paper determines the structures of ARE ABCF-ribosome complexes from three Gram-positive bacteria and proposes a model for antibiotic resistance mechanisms.

bioRxiv · Nov 24, 2020Microbiology

Tautomerization constrains the accuracy of codon-anticodon decoding

A. Kazantsev, Z. Ignatova

The paper investigates how tautomerization affects codon-anticodon decoding accuracy and develops a model explaining the role of the ribosomal A-site in this process.

bioRxiv · Oct 19, 2020Biophysics

Structural basis for bacterial ribosome quality control

C. Crowe-McAuliffe, H. Takada, V. Murina, C. Polte, S. Kasvandik, T. Tenson, Z. Ignatova, G. C. Atkinson, D. N. Wilson, V. N. Hauryliuk

This study identifies RqcH and YabO as factors mediating C-terminal tailing in Bacillus subtilis through cryo-EM structures showing their role in tRNA movement without mRNA or small subunit.

bioRxiv · Sep 3, 2020Biochemistry

Genome-wide effects of the antimicrobial peptide apidaecin on translation termination

K. Mangano, T. FLorin, X. Shao, D. Klepacki, I. Chelysheva, Z. Ignatova, Y. Gao, A. Mankin, N. Vazquez-Laslop

This study shows that the antimicrobial peptide apidaecin inhibits translation by arresting ribosomes at stop codons and causing stop codon bypass, leading to C-terminal extensions on proteins.

bioRxiv · May 17, 2020Biochemistry