PathologybioRxivPreprint
Macrophage-targeted DNA methyltransferase inhibitor SGI-1027 decreases atherosclerosis in ApoE-null mice
A. C. Marquez-Sanchez, A. Manzanares-Guzman, R. Carriles-Jaimes…·S. Zaina
This study shows that macrophage-targeted DNA methyltransferase inhibitor SGI-1027 reduces atherosclerosis in ApoE-null mice by altering macrophage cytokine profiles and reducing atherosclerotic burden.
DOI 10.1101/2023.08.22.554347