N1-methyladenine safeguards against aberrant RNA-protein association during proteostasis stress
M. Alriquet, G. Calloni, A. Martinez-Limon, R. Delli Ponti, G. Hanspach, M. Hengesbach, G. G. Tartaglia, R. M. Vabulas
The paper shows that N1-methyladenine (m1A) protects mRNAs from aberrant RNA-protein interactions during proteostasis stress, such as heat shock and amyloidogenesis.
bioRxiv · Jun 12, 2019 · PreprintCell Biology