Drugs Form Ternary Complexes with Human Liver Fatty Acid Binding Protein (FABP1) and FABP1 Binding Alters Drug Metabolism
K. C. B. Yabut, A. Martynova, A. Nath, B. P. Zercher, M. F. Bush, N. Isoherranen
This study shows drugs form ternary complexes with human FABP1 and that FABP1 binding alters drug metabolism by affecting CYP2C9 activity.
bioRxiv · Jan 17, 2024Pharmacology & Toxicology