E2F1 Drives Breast Cancer Metastasis by Regulating the Target Gene FGF13 and Altering Cell Migration
D. P. Hollern, M. R. Swiatnicki, J. P. Rennhack, S. A. Misek, B. C. Matson, A. McAuliff, K. A. Gallo, K. M. Caron, E. R. Andrechek
This study identifies E2F1 as a master regulator of metastasis by upregulating Fgf13, which promotes breast cancer cell migration and pulmonary metastasis.
bioRxiv · Jun 13, 2019Cancer Biology