MicrobiologybioRxiv
Intracellular Group A Streptococcus induces Golgi fragmentation to impair host defenses through Streptolysin O and NAD-glycohydrolase
T. Nozawa, J. Iibushi, H. Toh…·I. Nakagawa
This study shows that intracellular Group A Streptococcus uses SLO and Nga to fragment the Golgi complex, impairing host defenses and promoting bacterial pathogenesis.
DOI 10.1128/mbio.01974-20