Intracellular Group A Streptococcus induces Golgi fragmentation to impair host defenses through Streptolysin O and NAD-glycohydrolase
T. Nozawa, J. Iibushi, H. Toh, A. Minowa-Nozawa, K. Murase, C. Aikawa, I. Nakagawa
This study shows that intracellular Group A Streptococcus uses SLO and Nga to fragment the Golgi complex, impairing host defenses and promoting bacterial pathogenesis.
bioRxiv · Jul 16, 2020Microbiology