Cytokine receptor-Eb1 interaction couples cell polarity and fate during asymmetric cell division
Y. M. Yamashita, C. Chen, A. Mordovanakis, A. J. Hunt, M. Mayer, R. Cummings, D. Sept
The paper identifies a novel mechanism where the cytokine receptor Dome interacts with Eb1 to regulate spindle orientation in Drosophila GSCs, linking cell polarity to fate without involving the JAK-STAT pathway.
bioRxiv · Dec 4, 2017Cell Biology