Author

A. N. Hume

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Organism:mouse· 1 Organism:zebrafish· 1

Frequent Co-Authors

A. K. Stainthorp· 1 shared A. Oberhofer· 1 shared C. L. Robinson· 1 shared D. A. Briggs· 1 shared D. A. Elbe· 1 shared D. Zimmermann· 1 shared E. Brames· 1 shared E. Kerkhoff· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCell Biology

A. K. Stainthorp

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2 papers

Recent·Most cited

How to navigate the myosin-V motor through the actin network

P. Spieler, A. Oberhofer, D. Zimmermann, E. Brames, A. N. Hume, Z. Oekten

This paper shows that phosphorylation regulates myosin-Va switching behavior at actin-actin crossings via its adaptor protein Mlph, enabling precise cargo navigation in amphibians but not in zebrafish.

bioRxiv · Mar 11, 2020 · PreprintBiochemistry

Rab27a co-ordinates actin-dependent transport by controlling organelle-associated motors and track assembly proteins.

N. Alzahofi, C. L. Robinson, T. Welz, E. L. Page, D. A. Briggs, A. K. Stainthorp, J. Reekes, D. A. Elbe, F. Straub, E. W. Tate, P. S. Goff, E. V. Sviderskaya, M. Cantero, L. Montoliu, M. Bailly, , A. N. Hume

The paper shows Rab27a recruits SPIRE1/2 to melanosomes, linking motor and track assembly proteins to enable long-range organelle transport via actin tracks.

bioRxiv · May 3, 2018Cell Biology