Author

D. A. Briggs

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Approach:comparative / phylogenetic analysis· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Organism:zebrafish· 1

Frequent Co-Authors

E. Kerkhoff· 2 shared F. Straub· 2 shared N. Alzahofi· 2 shared T. Welz· 2 shared A. Hume· 1 shared A. K. Stainthorp· 1 shared A. N. Hume· 1 shared A. Samol-Wolf· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersCell Biology

E. Kerkhoff

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A time-resolved Forster resonance energy transfer assay to investigate inhibitor binding to ABCG2

J. I. Mitchell-White, D. A. Briggs, S. J. Mistry, H. A. Mbiwan, B. Kellam, N. D. Holliday, S. J. Briddon, I. D. Kerr

The paper introduces a TR-FRET assay to measure inhibitor binding to ABCG2 and confirms NBD dimerization correlates with a shift in inhibitor affinity.

bioRxiv · Oct 27, 2023 · PreprintBiochemistry

Animal evolution coincides with a novel degree of freedom in exocytic transport processes

M. Kollmar, T. Welz, F. Straub, N. Alzahofi, K. Hatje, D. A. Briggs, A. Samol-Wolf, P. Burkhardt, A. Hume, E. Kerkhoff

The paper identifies the origin of a novel exocytic transport mechanism in early animal evolution, tracing SPIRE function to choanoflagellates and showing its role in coordinating actin/myosin forces for cellular communication.

bioRxiv · Mar 28, 2019 · PreprintCell Biology

Rab27a co-ordinates actin-dependent transport by controlling organelle-associated motors and track assembly proteins.

N. Alzahofi, C. L. Robinson, T. Welz, E. L. Page, D. A. Briggs, A. K. Stainthorp, J. Reekes, D. A. Elbe, F. Straub, E. W. Tate, P. S. Goff, E. V. Sviderskaya, M. Cantero, L. Montoliu, M. Bailly, , A. N. Hume

The paper shows Rab27a recruits SPIRE1/2 to melanosomes, linking motor and track assembly proteins to enable long-range organelle transport via actin tracks.

bioRxiv · May 3, 2018Cell Biology