Ulcerative colitis is characterized by amplified acute inflammation with delayed resolution
R. Wysoczanski, A. C. Kendall, M. Motwani, R. Vega, F. Z. Rahman, S. McCartney, S. L. Bloom, A. Nicolaou, D. W. Gilroy, A. W. Segal, D. J. Marks
This study shows that ulcerative colitis patients have exaggerated and prolonged inflammatory responses to bacterial injection, which are mitigated by 5-aminosalicylates through pro-resolution lipid pathways.
bioRxiv · Dec 10, 2019 · PreprintImmunology