Data-Dependent Acquisition with Precursor Coisolation Improves Proteome Coverage and Measurement Throughput for Label-Free Single-Cell Proteomics
T. Truong, S. M. Johnston, K. Webber, H. Boekweg, C. Lundgren, Y. Liang, A. Nydegger, X. Xie, S. H. Payne, R. T. Kelly
This paper introduces WWA, a data acquisition method that improves proteome coverage and throughput in single-cell proteomics by co-isolating and fragmenting additional precursors.
bioRxiv · Oct 18, 2022Cell Biology