Author

A. Ottolenghi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:diffusion model· 1 Assay:flow cytometry· 1 Organism:mouse· 1

Frequent Co-Authors

A. Bruno· 1 shared A. J. Arribas· 1 shared A. Kuzmina· 1 shared A. M. Chiaravalli· 1 shared A. Rinaldi· 1 shared B. Rosental· 1 shared C. Leoni· 1 shared D. Korovin· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperImmunology

A. Bruno

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

P681 mutations within the polybasic motif of spike dictate fusogenicity and syncytia formation of SARS CoV-2 variants

A. Kuzmina, N. Atari, A. Ottolenghi, D. Korovin, I. Cohen Lass, B. Rosental, E. Rosenberg, M. Mandelboim, R. Taube

This study investigates how mutations at position 681 of the SARS-CoV-2 spike protein affect viral fusogenicity and syncytia formation across variants.

bioRxiv · Apr 26, 2022 · PreprintMicrobiology

IL-1α secreted by subcapsular sinus macrophages promotes melanoma metastasis in the sentinel lymph node by upregulating STAT3 signaling in the tumor.

T. Virgilio, J. Bordini, G. Sartori, I. Latino, D. Molina-Romero, C. Leoni, M. Akhmedov, A. Rinaldi, A. J. Arribas, D. Morone, S. M. S. Jafari, M. Bersudsky, A. Ottolenghi, I. Kwee, A. M. Chiaravalli, , S. F. Gonzalez

This study shows that IL-1α from subcapsular sinus macrophages promotes melanoma metastasis by enhancing STAT3 signaling in tumor cells, and blocking this pathway reduces metastasis.

bioRxiv · Oct 11, 2021 · PreprintImmunology

Radiation-induced cell cycle perturbations: acomputational tool validated with flow-cytometrydata

L. LONATI, S. Barbieri, I. Guardamagna, A. Ottolenghi, G. Baiocco

The paper presents a computational model of radiation-induced cell cycle perturbations validated with flow cytometry data from human lung fibroblasts.

Scientific Reports · Jan 13, 2021Peer-reviewedBiophysics