Subcapsular sinus macrophage sensing of extracellular matrix rigidity alters membrane topography and immune complex mobility
M. Iliopoulou, A. T. Bajur, H. C. McArthur, C. Coyle, F. Ajao, R. Köchl, A. P. Cope, K. M. Spillane
This study shows that subcapsular sinus macrophages (SSMs) sense ECM rigidity, altering their membrane topography and immune complex mobility through actin cytoskeleton changes.
bioRxiv · Dec 2, 2022 · PreprintImmunology