The J domain of sacsin disrupts intermediate filament assembly
A. Dabbaghizadeh, A. Pare, Z. Cheng-Boivin, R. Dagher, S. Minotti, M.-J. Dicaire, B. Brais, J. C. Young, H. D. Durham, B. J. Gentil
This study shows that the J domain of sacsin disrupts intermediate filament assembly, with therapeutic potential in ARSACS.
bioRxiv · Jul 14, 2021 · PreprintCell Biology