Author

J. C. Young

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Organism:human· 3 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

M. Broncel· 2 shared M. Treeck· 2 shared A. Dabbaghizadeh· 1 shared A. Hunt· 1 shared A. Jobling· 1 shared A. Pare· 1 shared B. A. Wallbank· 1 shared B. Brais· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersMicrobiology

M. Broncel

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Expansion of in vitro Toxoplasma gondii cysts using enzymatically enhanced ultrastructure expansion microscopy

K. Bondarenko, F. Limoge, K. Pedram, M. Gissot, J. C. Young

This paper introduces an enzymatic digestion step using StcE to enable ultrastructure expansion microscopy of Toxoplasma gondii cysts, allowing detailed super-resolution analysis of the chronic infection stage.

bioRxiv · Apr 24, 2024 · PreprintMicrobiology

Toxoplasma gondii ROP1 subverts murine and human innate immune restriction

S. Butterworth, F. Torelli, E. J. Lockyer, J. Wagener, O.-R. Song, M. Broncel, M. Russell, J. C. Young, M. Treeck

The paper identifies 22 secreted proteins contributing to Toxoplasma gondii growth in vivo and shows ROP1's role in evading murine and human innate immunity.

bioRxiv · Mar 21, 2022Microbiology

The J domain of sacsin disrupts intermediate filament assembly

A. Dabbaghizadeh, A. Pare, Z. Cheng-Boivin, R. Dagher, S. Minotti, M.-J. Dicaire, B. Brais, J. C. Young, H. D. Durham, B. J. Gentil

This study shows that the J domain of sacsin disrupts intermediate filament assembly, with therapeutic potential in ARSACS.

bioRxiv · Jul 14, 2021 · PreprintCell Biology

Fractalkine-induced microglial vasoregulation occurs within the retina and is altered early in diabetic retinopathy

S. A. Mills, A. Jobling, M. A. Dixon, B. V. Bui, K. A. Vessey, J. A. Phipps, U. Greferath, G. Venables, V. H. Y. Wong, C. H. Y. Wong, Z. He, F. Hui, J. C. Young, J. Tonc, E. Ivanova, , E. L. Fletcher

This study shows microglia regulate retinal capillary constriction via fractalkine-Cx3cr1 signaling and RAS pathway, with dysfunction occurring early in diabetic retinopathy.

bioRxiv · Jun 15, 2020Cell Biology

Global profiling of myristoylation in Toxoplasma gondii reveals key roles for lipidation in CDPK1 and MIC7 function

M. Broncel, C. Dominicus, A. Hunt, B. A. Wallbank, S. Federico, J. C. Young, M. Treeck

The paper identifies 65 myristoylated proteins in Toxoplasma gondii, highlighting roles for myristoylation in CDPK1 signaling and MIC7 function during host cell invasion.

bioRxiv · Jul 30, 2019 · PreprintMicrobiology