Author

A. Parras

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Assay:DNA methylation· 1

Frequent Co-Authors

A. Haghani· 2 shared A. Ocampo· 2 shared C. Mrabti· 2 shared R. Brooke· 2 shared S. Horvath· 2 shared A. Alonso-Calleja· 1 shared A. Seluanov· 1 shared A. Vilchez-Acosta· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersPhysiology

A. Haghani

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Loss of H3K9 trimethylation leads to premature aging

C. Mrabti, N. Yang, G. Desdin-Mico, A. Alonso-Calleja, A. Vilchez-Acosta, S. Pico, A. Parras, Y. Piao, L. Schoenfeldt, S. Luo, A. Haghani, R. Brooke, M. d. C. Maza, C. Branchina, C. Yacoub Maroun, , A. Ocampo

This study shows that loss of H3K9me3 in adult mice leads to premature aging, characterized by reduced lifespan, frailty, and accelerated epigenetic aging.

bioRxiv · Jul 24, 2024 · PreprintPhysiology

Initiation phase cellular reprogramming ameliorates DNA damage in the ERCC1 mouse model of premature aging.

P. T. Paine, C. Rechsteiner, F. Morandini, G. Desdin Mico, C. Mrabti, A. Parras, A. Haghani, R. Brooke, S. Horvath, A. Seluanov, V. Gorbunova, A. Ocampo

The paper uses partial cellular reprogramming to reduce DNA damage in an ERCC1 mouse model of premature aging, showing restoration of the epigenetic clock and DNA repair processes.

bioRxiv · May 12, 2023Cell Biology