Ion currents through Kir potassium channels are gated by anionic lipids.
R. Jin, S. He, K. A. Black, O. B. Clarke, D. Wu, J. R. Bolla, P. Johnson, A. Periasamy, A. Wardak, P. Czabotar, P. M. Colman, C. V. Robinson, D. Laver, B. J. Smith, J. M. Gulbis
The paper shows anionic lipids gate potassium conduction through Kir channels by interacting with the internal gate via fatty acyl tails.
bioRxiv · Sep 21, 2021Biochemistry