PIK3IP1/TrIP restricts activation of T cells through inhibition of PI3K/Akt
U. Uche, A. L. Szymczak-Workman, S. Grebinoski, A. Piccirillo, L. M. D'Cruz, L. P. Kane
This study identifies TrIP as a negative regulator of T cell activation by inhibiting PI3K, showing its role in immune response and potential as a therapeutic target.
bioRxiv · Nov 6, 2017Immunology