A. Politi

Plk1 inhibition delays mitotic entry revealing prophase-specific changes to the phosphoproteome

This study shows that Plk1 inhibition delays mitotic entry, revealing prophase-specific phosphoproteome changes and highlighting Plk1's role in the prophase to prometaphase transition.

Real-time chromatin dynamics at the single gene levelduring transcription activation

This study uses real-time imaging to show that transcription initiation rapidly confines a gene's chromatin domain, independent of RNA polymerase elongation.

Mechanism of Nuclear Movements in a Multinucleated Cell

The paper models nuclear movement in multinucleated fungal hyphae using 3D simulations, showing how microtubules and dynein motors drive oscillatory motion and prevent nuclear clustering.