Author

A. R. Damodaran

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

A. Bhagi-Damodaran· 2 shared E. A. Apiche· 1 shared E. Yee· 1 shared H. Ouyang· 1 shared J. A. G. da Costa· 1 shared P. Windsor· 1 shared Y. Chen· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 13 mutual co-author links

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2 shared papersBiochemistry

A. Bhagi-Damodaran

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2 papers

Recent·Most cited

Oxygen affinities of DosT and DosS sensor kinases with implications for hypoxia adaptation in Mycobacterium tuberculosis

E. A. Apiche, E. Yee, A. R. Damodaran, A. Bhagi-Damodaran

This study measures the oxygen binding affinities of DosT and DosS kinases in Mycobacterium tuberculosis, revealing stronger affinities than previously reported and linking them to hypoxia adaptation stages.

bioRxiv · Feb 26, 2024 · PreprintBiochemistry

Gas tunnel engineering of prolyl hydroxylasereprograms hypoxia signaling in cells

P. Windsor, H. Ouyang, J. A. G. da Costa, A. R. Damodaran, Y. Chen, A. Bhagi-Damodaran

This study reprograms hypoxia signaling by engineering PHD2 to enhance its catalytic efficiency, leading to reduced HIF-1 and hypoxia response transcripts under low oxygen conditions.

bioRxiv · Aug 7, 2023Biochemistry