ImmunologybioRxiv
Interferons Reshape the 3D Conformation and Accessibility of Macrophage Chromatin
E. Platanitis, S. Güner, A. R. S. J. Geetha…·T. Decker
This study shows that type I and type II interferons induce similar epigenomic and transcriptional changes in macrophages, including 3D chromatin rearrangements and increased DNA accessibility at ISG loci.